CNS Drug Brain Exposure Reasoning Dataset
- Records
- 5000
- Size
- 0.4GB
- Format
- JSON
- Provider
MOBIUSI INC- Updated
- v1.02026-11-04
This question-answer dataset focuses on comparing brain exposure among candidate small molecules for central nervous system drug discovery. Samples provide information such as physicochemical properties, transporter data, plasma and brain tissue exposure, and unbound drug fractions, and require analysis of likely brain exposure, distribution-limiting factors, and the distinction between measured evidence and predictions or inferences. It supports reasoning supervised fine-tuning, drug development question answering, and evidence-provenance evaluation.
Overview
Dataset Insights
Preview
Sample Examples
Schema
Technical Specifications
| Field | Type | Description |
|---|---|---|
| file_name | string | File name |
| source_text | string | Original question and supplied candidate-drug information, including physicochemical properties, transporter data, plasma and brain exposure, and unbound fractions. |
| limiting_factors | string | Identify and explain factors that may constrain brain distribution, such as physicochemical properties, transporter effects, or unbound drug fraction. |
| reasoning_answer | string | Provide a concise, integrated answer that explains the comparison using the supplied evidence and avoids unsupported conclusions. |
| evidence_provenance | string | Distinguish directly measured evidence from predicted or inferred information, noting uncertainty where appropriate. |
| exposure_comparison | string | Compare the candidates' likely brain exposure and state the conclusion supported by the supplied evidence. |
Trust
Compliance Statement
Authorization Type
Proprietary - Commercial AI Training License (No Redistribution)
Commercial Use
Requires exclusive subscription or authorization contract (monthly or per-invocation charging)
Privacy and Anonymization
No PII, no real company names, simulated scenarios follow industry standards
Compliance System
Compliant with China's Data Security Law / EU GDPR / supports enterprise data access logs
FAQ
Frequently Asked Questions
- What information does the dataset contain?
- Question-answer samples provide candidate small-molecule properties, transporter information, plasma and brain tissue exposure, and unbound drug fractions. The reasoning answers address brain exposure comparisons, limiting factors, and evidence provenance.
- Which research and model tasks can it support?
- It can support CNS drug candidate comparisons, brain distribution analysis, drug discovery question answering, and reasoning supervised fine-tuning. It can also help evaluate whether a model explains conclusions from supplied information and distinguishes measured evidence from predictions.
- How can I obtain the dataset?
- Check the dataset product page for available download methods, delivery formats, and access conditions. The product page and delivery documentation specify what is provided.
- What should I consider regarding data quality and licensing?
- Samples emphasize evidence-grounded reasoning and distinguish measured information from predictions or inferences; users should still verify the original evidence and its uncertainty. Check the applicable product license for permitted uses, including commercial use. The content is not a substitute for pharmacological experiments or expert review.
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Cite this Work
@dataset{Mobiusi2026,
title={CNS Drug Brain Exposure Reasoning Dataset},
author={MOBIUSI INC},
year={2026},
url={https://www.mobiusi.com/datasets/3811dd98b27cd1c756b865ec353ae5a5?dataset_scene_id=4},
urldate={2026-10-21},
keywords={CNS drugs,brain exposure data,brain distribution reasoning,small-molecule drugs,blood-brain barrier,transporter analysis,drug discovery QA,reasoning SFT},
version={1.0}
}Using this in research? Please cite us.